State Key Laboratory Cultivation Base of Research,Prevention and Treatment for Oral Diseases

National Key Laboratory for Research and Prevention of Oral Diseases (Incubation Site)

It is currently the largest, most advanced, and most comprehensive oral medicine research base in the province. Originally the Tissue Engineering Laboratory of the School of Stomatology at Nanjing Medical University, it was renamed the "Institute of Stomatology, Nanjing Medical University" in 2004. In 2011, it was listed as the "Key Laboratory for Oral Disease Research, Nanjing Medical University," and in 2014, it was approved as the "Jiangsu Provincial Key Laboratory for Oral Disease Research." In the 2020 evaluation by the Jiangsu Provincial Department of Education (among 101 laboratories, 15 were rated as "excellent"), it received an excellent rating. In 2024, it was successfully reorganized and upgraded to the "National Key Laboratory for Research and Prevention of Oral Diseases (Incubation Site)," making it the sole national-level key laboratory incubation site for oral medicine research in Jiangsu Province.

Over two decades of development, the laboratory has established several research-specific experimental areas, including oral molecular epidemiology, oral microbiology, oral molecular biology, oral tissue engineering, and oral materials science. It houses multiple shared research platforms such as the Immunology and Single-Cell Omics Platform, Optical Imaging Platform, Developmental Experiment Platform, Pathology Platform, and Tissue Sample Repository. It has also acquired a suite of advanced domestic and international precision instruments and equipment, valued at over 50 million yuan. The laboratory conducts varieties of oral medicine research projects and annually trains over 100 master's students and more than 20 doctoral students, making it the largest and most comprehensive oral medicine research and education base in the province for training graduate students in oral medicine.

The laboratory focuses on key technological issues in the field of oral medicine, conducting research in four directions: the pathogenesis and prevention of dentofacial deformities, the homeostasis and regenerative remodeling mechanisms of oral inflammatory diseases, the pathogenesis and prevention of head and neck tumors, and the repair and functional reconstruction of dentofacial defects. It has developed unique specialties and strengths in oral medicine, adhering to the integration of basic research with clinical application to promote the medical practice transformation of research outcomes.